The influence of the global financial crisis on economic cooperation between the two countries and prospects for trade relations were the subjects of discussion.
The presidents also reaffirmed their readiness to continue cooperating on pressing international and regional issues.
President Medvedev stressed that regular meetings will help develop the Russian-Pakistani dialogue.
Mr Medvedev and Mr Zardari had already met at the meeting of the Council of Heads of Member States of the Shanghai Cooperation Organisation in Yekaterinburg in June 2009.